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Vatelizumab (CAT#: TAB-251)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ITGA2 Recombinant Antibody TAB-251 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to ITGA2. Vatelizumab is an immunomodulator. It binds to integrin alpha 2
  • Target
  • ITGA2
  • Type
  • IgG4 - kappa
  • Immunogen
  • Whole human keratinocytes.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
  • CAS
  • 1238217-55-4
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G4-kappa, anti-[Homo sapiens ITGA2 (integrin alpha 2, CD49b, GPIa, subunit of the alpha2beta1 integrin (VLA-2, collagen receptor))], humanized monoclonal antibody
  • Predicted N terminal
  • H chain: QVQLQES; L chain: DIVMTQS
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
  • Function
  • collagen binding; protein binding; receptor activity;
  • Synonyms
  • ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49B; integrin alpha-2; CD49b; integrin alpha 2; collagen receptor; VLA-2 subunit alpha; platelet antigen Br; platelet glycoprotein Ia; platelet glycoprotein GPIa; CD49 antigen-like family member B; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; BR; GPIa; VLA-2; VLAA2; BDPLT9;

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